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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCC
All Species:
14.24
Human Site:
T1377
Identified Species:
26.11
UniProt:
P43146
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P43146
NP_005206.2
1447
158457
T1377
P
G
P
T
L
P
K
T
H
V
K
T
A
S
L
Chimpanzee
Pan troglodytes
XP_512137
1447
158305
T1377
P
G
P
T
L
P
K
T
H
V
K
T
A
S
L
Rhesus Macaque
Macaca mulatta
XP_001093533
1612
176214
Q1539
S
T
P
L
L
S
Q
Q
A
L
N
H
H
I
H
Dog
Lupus familis
XP_541094
1486
162271
T1416
P
G
P
T
L
P
K
T
H
V
K
T
A
S
L
Cat
Felis silvestris
Mouse
Mus musculus
P70211
1447
158281
T1377
P
G
P
T
L
P
K
T
H
V
K
T
A
S
L
Rat
Rattus norvegicus
P97603
1377
150619
H1308
L
S
Q
Q
A
L
N
H
H
L
H
S
V
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509438
1546
169614
A1476
T
G
P
N
L
P
K
A
Q
V
K
T
A
S
L
Chicken
Gallus gallus
Q90610
1443
158032
Q1369
P
S
T
P
L
L
T
Q
Q
A
P
S
H
P
V
Frog
Xenopus laevis
NP_001079254
1427
156515
A1357
T
G
S
G
L
S
K
A
Q
V
K
T
A
S
L
Zebra Danio
Brachydanio rerio
Q2EY14
1149
126278
S1079
L
Q
G
L
F
G
P
S
G
G
D
S
E
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_725185
1375
151646
R1306
H
T
P
A
V
T
I
R
P
Q
N
Q
S
P
Y
Honey Bee
Apis mellifera
XP_001122444
1492
165549
V1420
K
H
V
S
Q
V
T
V
R
P
T
M
S
G
S
Nematode Worm
Caenorhab. elegans
NP_491664
1415
154419
K1346
S
D
A
G
E
S
D
K
K
S
G
E
C
M
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
46.6
93.4
N.A.
96.4
51.4
N.A.
83.2
51.9
81.4
25.3
N.A.
32.9
32.5
28.5
N.A.
Protein Similarity:
100
99.8
63.4
95.2
N.A.
98.3
69.3
N.A.
88.7
71.1
89.7
40.8
N.A.
51.4
50.5
47.2
N.A.
P-Site Identity:
100
100
13.3
100
N.A.
100
6.6
N.A.
73.3
13.3
60
0
N.A.
6.6
0
0
N.A.
P-Site Similarity:
100
100
26.6
100
N.A.
100
20
N.A.
73.3
26.6
60
13.3
N.A.
20
13.3
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
8
0
0
16
8
8
0
0
47
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
8
0
0
0
0
8
0
0
0
8
0
0
0
0
% D
% Glu:
0
0
0
0
8
0
0
0
0
0
0
8
8
0
8
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
47
8
16
0
8
0
0
8
8
8
0
0
16
0
% G
% His:
8
8
0
0
0
0
0
8
39
0
8
8
16
0
8
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% I
% Lys:
8
0
0
0
0
0
47
8
8
0
47
0
0
8
0
% K
% Leu:
16
0
0
16
62
16
0
0
0
16
0
0
0
0
47
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% M
% Asn:
0
0
0
8
0
0
8
0
0
0
16
0
0
0
0
% N
% Pro:
39
0
54
8
0
39
8
0
8
8
8
0
0
16
0
% P
% Gln:
0
8
8
8
8
0
8
16
24
8
0
8
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% R
% Ser:
16
16
8
8
0
24
0
8
0
8
0
24
16
47
16
% S
% Thr:
16
16
8
31
0
8
16
31
0
0
8
47
0
0
8
% T
% Val:
0
0
8
0
8
8
0
8
0
47
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _